DNA Primase: A Key Enzyme in DNA Replication (P15560)

Target Name: DNA primase

NCBI ID: P15560

DNA primase

Other Name(s): None

DNA Primase: A Key Enzyme in DNA Replication

DNA primase is a protein that plays a critical role in the replication of DNA in eukaryotic cells. It is a key enzyme in the DNA replication process, and is essential for the formation of a double helix in the replicated DNA.

DNA primase is a protein that is expressed in all eukaryotic cells, and is highly conserved across different species. It is a single-stranded protein that has a molecular weight of approximately 18 kDa. DNA primase is localized to the nucleus of the cell, and is involved in the initiation of DNA replication.

One of the key functions of DNA primase is to recruit the template RNA to the replication complex. This RNA is then cleaved by an enzyme called DNA polymerase, which is the enzyme responsible for copying the template RNA to the new DNA strand. DNA primase is also involved in the regulation of DNA replication, by ensuring that the correct number of copies of the template RNA are synthesized.

Another function of DNA primase is to ensure that the double helix is 鈥嬧?媐ormed in the correct orientation. DNA replication starts from the 5' end of the DNA strand, and DNA primase helps to ensure that the 5' end is correctly labeled with a complementary base . This ensures that the new DNA strand will be in the correct direction, and will have the same sequence as the original DNA strand.

DNA primase is a protein that is being targeted by researchers as a potential drug target or biomarker. One of the reasons for this is that DNA replication is a highly regulated process, and changes in the levels of DNA primase activity can have a significant impact on the replication of DNA in cells. Additionally, DNA primase is a protein that is expressed in all eukaryotic cells, making it a potential biomarker for a wide range of diseases.

In addition to its role in DNA replication, DNA primase is also involved in the regulation of gene expression. It has been shown to play a role in the regulation of gene expression in various organisms, including bacteria and yeast. Additionally, DNA primase has been shown to play a role in the regulation of cellular processes such as cell growth, cell division, and apoptosis.

In conclusion, DNA primase is a critical enzyme in the replication of DNA in eukaryotic cells. It is a protein that is highly conserved across different species, and is involved in the initiation, regulation, and completion of DNA replication. DNA primase is also being targeted as a potential drug target or biomarker, due to its involvement in the regulation of DNA replication and various cellular processes. Further research is needed to fully understand the role of DNA primase in eukaryotic cells, and to determine its potential as a drug target or biomarker.

Protein Name: DNA Primase

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